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China, Chinese Folinic Acid Calcium Salt CAS 1492-18-8 Leucovorin Calcium CF1 Industrial Products Supplier Manufacturer Details, price list catalog:
China Industrial Products Supplier Manufacturer List Catalog
Inorganic SaltOther Inorganic SaltsFolinic Acid Calcium Salt1492-18-8
Ningbo Surest Chemical Co., Ltd.
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Product Description Product DescriptionNameLeucovorin calciumSynonymsFolinic acid calcium salt; N-(4-(((2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid calcium saltMolecular FormulaC20H21N7O7.CaMolecular Weight511.51CAS Registry Number1492-18-8EINECS216-082-8 Main Uses: This product is a white to slightly yellow crystalline or amorphous powder; Odorless.This product dissolves in water and is almost insoluble in ethanol or ether; Dissolve in 0.1mol/sodium hydroxide solution.1. It is mainly used as an antidote to folate antagonists (such as trimethoprim, etc.), and is often used to prevent serious toxic effects caused by large doses or excessive treatment of 2, for folic acid treatment of the following diseases, such as oral diarrhea, protein-energy malnutrition (malnutrition), pregnancy or infancy caused by megaloblastic anemia is not effective.3, as an adjunct treatment for colon cancer and rectal cancer.4. Combined with 5-FU, it is used to treat digestive tract tumors or other 5-FU-sensitive tumors. The combination of high-dose CF and 5-FU (LF regimen) is the basic regimen for the treatment of colon and rectal cancer.5, used in children leukemia, lymphoma and osteosarcoma and other large dose MTX treatment rescue. 1. Detoxification effectMethotrexate detoxificationDetoxification with other folate antagonists2. Tumor treatment adjuvantEnhance chemotherapy efficacyPreventing bone marrow suppression3. Treatment of hematological diseasesMegaloblastic anemia4. Other usesPrevention of Fetal Neural Tube DefectsCardiovascular protection SpecificationItemsSpecificationsAppearanceWhite or light yellow hygroscopic powderIdentification IRConforms to the Reference SpectrumCalcium saltmust give a positive reactionAppearance of solutionClear and colorlessPH7.5-8.5Residue on ignitionEthanol≤3.0%Acetone≤0.5%Methanol≤0.3%Related substancesImpurity A≤0.3%Impurity E≤0.3%Impurity F≤0.2%Impurity I≤0.2%Impurity H≤0.5%Unknown impurities≤0.2%Total impurities≤1.5%Chloride (Cl)≤0.5%Water10.0%-17.0%Heavy metals≤50 ppmCalcium7.54%-8.14%Calcium folinate97.0-102.0%Total aerobic microbial count≤1000cfu/gTotal combined yeast and mold count≤100cfu/gEscherichia coliAbsent/gSalmonellaAbsent/gS.aureusAbsent/g Detailed Photos FAQQuestion 1: Can I get samples?Answer: Yes,you can get free samples of our most products,while the courier cost will be borne by the buyers.Question 2: What's your MOQ?Answer: For a express delivery order,the MOQ is usually 100 g~1 kg;for an air transport order or sea delivery order ,the MOQ is usually 25 kgs.Question 3: What's your delivery time?Answer: Orders shipped by express delivery,the delivery time is usually 5~7 working days;Orders shipped by air transport,usually around 7~10 working days; Orders shipped by sea , usually around 2~3 working weeks.Question 4: What are the different payment methods?Answer: We usually accept T/T, L/C and Western Union.Question 5: How do you treat quality complaint?We take quality very seriously, it is one of the founding principles of our business. If the quality problem actually exists, we will replace with qualified goods or refund the money.
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