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China, Chinese High Absorption and Bioavailability Health Supplement (DHB) 98% Dihydroberberine1 Industrial Products Supplier Manufacturer Details, price list catalog:
China Industrial Products Supplier Manufacturer List Catalog
Organic ChemicalsOrganic IntermediateDihydroberberineDihydroberberine 98%
Xi'an Lyphar Biotech Co., Ltd.
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Product Description High Absorption and Bioavailability Health Supplement (DHB) 98% Dihydroberberine Product nameDihydroberberine CAS No4483-15-8SolubilitySoluble to 57.46 mg/l in water;Soluble in DMSOAssay98% minMOQ50gMolrcular Formular Dihydroberberine (DHB) is a bioactive form of berberine. When metabolizing berberine, our bodies form dihydroberberine. More specifically, enzymes such as cytochrome P450 reductases and other hepatic enzymes mainly convert the precursor substance, berberine, into dihydroberberine in the liver. Additionally, the microbes in the intestinal gut convert berberine to Dihydroberberine as well, proving that, at least in animals, the microbiome acts as an "organ" for Dihydroberberine production. The Key Difference: Absorption and BioavailabilityOne of the biggest limitations of traditional Berberine HCl is poor absorption. Studies show that only a small fraction-as little as 1%-of oral berberine is absorbed into systemic circulation. Much of it is metabolized by gut bacteria and excreted.Dihydroberberine, on the other hand, is far more efficient:Up to 5x more bioavailable than Berberine HClReaches peak plasma levels more quicklyRemains active longer in the bloodstreamRequires a lower dose to achieve the same effectDihydroberberine has been shown to:Lower blood glucose levelsReduce cholesterol and triglyceridesSupport gut healthModulate inflammationAid in weight control and fat metabolism
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